Tesamorelin

IMPORTANT: Read This Before Proceeding With Dosing
Go to the Prep & Injection Guide for proper reconstitution, syringe sizing, and injection protocols. Mistakes here can compromise your research.

Click here to read the Prep & Injection Guide

Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) that stimulates the release of human growth hormone (HGH). FDA-approved for body fat redistribution syndrome, Tesamorelin has shown powerful effects on fat loss, muscle preservation, nerve regeneration, and cognitive enhancement.

It is not a steroid and does not affect testosterone levels.

BENEFITS

• Reduces adipose fat tissue (especially in the abdomen and upper back)
• Targets visceral fat around internal organs (liver, stomach, intestines)
• Preserves and increases lean muscle mass
• Boosts metabolism and energy output
• Reduces cholesterol and triglycerides
• Supports nerve regeneration after injury
• Increases neurotransmitters tied to cognitive performance

POSSIBLE SIDE EFFECTS

• Injection site irritation (redness, swelling, itching)
• Muscle aches and pain
• Headache
• Nausea
• Diarrhea
• Sweating
• Carpal tunnel symptoms
• Edema
• Fluid retention

RARE BUT SERIOUS SIDE EFFECTS

• Diarrhea with fever and dehydration
• Shortness of breath
• Joint or muscle pain
• Numbness or tingling in the extremities
• May increase risk of Type-2 diabetes

INTERACTIONS

Tirzepatide and Tesamorelin should only be used together under close medical supervision for diabetics, due to the fact that they have opposing effects on blood glucose levels, which may reduce the effectiveness of diabetes management. Tesamorelin tends to raise blood sugar, while tirzepatide lowers it, potentially leading to unpredictable glucose control. In addition to the concerns regarding diabetics, taking Tesamorelin with Tirzepatide may make the Tirzepatide less effective.

CONTRAINDICATIONS

Do not use Tesamorelin if:

• You’ve had pituitary tumors or surgery
• You have an active malignancy
• You’re allergic to mannitol
• You’re pregnant or breastfeeding
• You’ve had hypothalamic-pituitary axis disruption
• You have a diagnosed pituitary disorder

DOSING

CYCLING: 12-16 week cycle followed by 4-8 week washout period. Shorter cycles will not yield tangible results- do not begin this product with the intention of “trying it out” for 3 or 4 weeks. This will not be effective. Each week should consist of 5 consecutive dosing days followed by 2
“rest” days.

TIMING: Dose at night, at least 90 minutes after your last meal.

RECONSTITUTION SOLUTION(S):

Hospira brand BAC water preferred (many companies do not maintain a known, consistent pH level like Hospira does)

.6% Acetic Acid Solution

Hospira brand BAC water is preferred because of the absolute consistency of its pH level- if the BAC water is a bit too acidic or too basic, peptides can lose their electrical charge, causing them to clump together. Extreme pH differences can denature the peptide, altering its structure and potentially rendering it ineffective.

Acetic Acid solution is mandatory in order to prevent gelling of the product

ADMINISTRATION: Subcutaneous Injection

Store at room temperature, in a cool, dry, dark location. This helps to prevent the peptide from gelling. Please note that storage at this temperature drastically decreases the length of time that you have to finish the vial. This is why we no longer carry vials larger than 10mg.

IMPORTANT NOTE CONCERNING POST-RECONSTITUTION STORAGE OF TESAMORELIN

TESAMORELIN: 10MG

Mix with .5mL (50 units) Acetic Acid until dissolved; then add 2.5mL (250 units) Bacteriostatic Water

Standard Protocol

30 units (1mg), 1x/day, 5 days/week

Maximum Protocol

60 units (2mg), 1x/day, 5 days/ week

TESAMORELIN: 20MG

Mix with 1mL (100 units) Acetic Acid solution until dissolved, then add 4mL (400 units) Bacteriostatic water

Standard Protocol

25 units (1mg) 1x/day, 5 days/week

Maximum Protocol

50 units (2mg) 1x/day, 5 days/’week

Stacking Suggestions

Tesamorelin stacks extremely well with other fat-burning and GH-boosting peptides:

• AOD-9604 – Targeted fat burning, especially abdominal
• CJC-1295 / Ipamorelin – Synergistic GH elevation for deeper fat loss and muscle growth
• GHK-Cu – Tissue regeneration and skin improvement
• MOTS-C – Boosts metabolic performance and ATP levels
• SS-31 – Mitochondrial repair and enhanced nerve healing
• L-Carnitine – Enhances fat metabolism during GH therapy

Fat loss stack: Tesamorelin + AOD-9604 + CJC-1295
Neuroregeneration stack: Tesamorelin + SS-31 + MOTS-C
Aesthetic stack: Tesamorelin + GHK-Cu + CJC-1295